If you group senders that you receive emails from in separate lists, you can reuse those lists within Custom AI Filters.
1.Create Lists
Under Email Management > Sender Lists you can create new lists.
You only need a title and a list of senders (which can be email addresses or domain names).
Email addresses are matches against this list, line by line.

2. Choose the list as filtering criteria
When you create the Custom Filter, choose one of the senders lists you added to be used as search criteria.
Sender email address will be matched against all items from your sender list.
